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Chapter 15: Cyclic peptides as privileged structures
Book PartAbstract:Palabras claves:Autores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Jad Y.E., Kruger H.G., Ramesh S.Fuentes:scopus2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis
ArticleAbstract: 2-MeTHF and CPME were evaluated as greener alternatives for the most employed solvents in peptide syPalabras claves:2-methyltetrahydrofuran, Cyclopentyl methyl ether, Green solvents, Peptide synthesis, Solid-phase peptide synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusDiethylphosphoryl-oxymab (DEPO-B) as a solid coupling reagent for amide bond formation
ArticleAbstract: A new phosphonium based coupling reagent DEPO-B has been synthesized from 5-(hydroxyimino)-1,3-dimetPalabras claves:coupling reagent, Diethylphosphoryl-OxymaB, Hydrolytic stability, Phosphonium salts, SOLUBILITYAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreen Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry
ArticleAbstract: DMF (N,N-dimethylformamide) is the most widely used solvent for Fmoc-SPPS, which is the conventionalPalabras claves:Fmoc, Green solvents, Peptide aggregation, Protecting groups, Solid-phase peptide synthesis, valerolactoneAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreen Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under Green Conditions
ArticleAbstract: N,N-Dimethylformamide (DMF), N-methyl-2-pyrrolidone, and dichloromethane (DCM) are the most widely uPalabras claves:2-MeTHF, Green Chemistry, Peptide aggregation, Polyethylene glycol resins, Solid-phase peptide synthesis, solid-phase synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreen Transformation of Solid-Phase Peptide Synthesis
ReviewAbstract: Peptides play key roles in medicinal chemistry, being found in therapeutics and diagnostic agents, aPalabras claves:Green Chemistry, Green solvents, Parallel synthesis, Peptide synthesis, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreen solid-phase peptide synthesis 4. γ-Valerolactone and N-formylmorpholine as green solvents for solid phase peptide synthesis
ArticleAbstract: Herein, we report the use of γ-valerolactone (GVL) and N-formylmorpholine (NFM) as DMF substitutes iPalabras claves:Green solvents, GVL, NFM, polystyrene resin, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitation of Peptides after Global Deprotection
ArticleAbstract: In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to incorporate thePalabras claves:2-MeTHF, Dipeptide formation, incorporation, precipitation, Racemization, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusEDC·HCl and Potassium Salts of Oxyma and Oxyma-B as Superior Coupling Cocktails for Peptide Synthesis
ArticleAbstract: Nowadays, DIC is the most widely used carbodiimide for solid-phase peptide synthesis, while EDC·HClPalabras claves:peptide coupling, Peptides, solid-phase synthesis, Steric hindrance, synthetic methodsAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusN-methylation in amino acids and peptides: Scope and limitations
ReviewAbstract: Active pharmaceutical ingbkp_redients (APIs) can be divided into two types, namely chemical and biolPalabras claves:cyclic peptides, NMAA, side-reactions, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A., Monaim S.A.H.A., Sharma A.Fuentes:scopus