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Chapter 15: Cyclic peptides as privileged structures
Book PartAbstract:Palabras claves:Autores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Jad Y.E., Kruger H.G., Ramesh S.Fuentes:scopus2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis
ArticleAbstract: 2-MeTHF and CPME were evaluated as greener alternatives for the most employed solvents in peptide syPalabras claves:2-methyltetrahydrofuran, Cyclopentyl methyl ether, Green solvents, Peptide synthesis, Solid-phase peptide synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusDiethylphosphoryl-oxymab (DEPO-B) as a solid coupling reagent for amide bond formation
ArticleAbstract: A new phosphonium based coupling reagent DEPO-B has been synthesized from 5-(hydroxyimino)-1,3-dimetPalabras claves:coupling reagent, Diethylphosphoryl-OxymaB, Hydrolytic stability, Phosphonium salts, SOLUBILITYAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreen Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry
ArticleAbstract: DMF (N,N-dimethylformamide) is the most widely used solvent for Fmoc-SPPS, which is the conventionalPalabras claves:Fmoc, Green solvents, Peptide aggregation, Protecting groups, Solid-phase peptide synthesis, valerolactoneAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusEDC·HCl and Potassium Salts of Oxyma and Oxyma-B as Superior Coupling Cocktails for Peptide Synthesis
ArticleAbstract: Nowadays, DIC is the most widely used carbodiimide for solid-phase peptide synthesis, while EDC·HClPalabras claves:peptide coupling, Peptides, solid-phase synthesis, Steric hindrance, synthetic methodsAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusN-methylation in amino acids and peptides: Scope and limitations
ReviewAbstract: Active pharmaceutical ingbkp_redients (APIs) can be divided into two types, namely chemical and biolPalabras claves:cyclic peptides, NMAA, side-reactions, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A., Monaim S.A.H.A., Sharma A.Fuentes:scopusOxyma-B, an excellent racemization suppressor for peptide synthesis
ArticleAbstract: Peptide-bond formation is a key process in the synthesis of peptide oligomers. Among the many coupliPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusLysine scanning of Arg<inf>10</inf>−teixobactin: Deciphering the role of hydrophobic and hydrophilic residues
ArticleAbstract: Teixobactin is a recently discovered antimicrobial cyclodepsipeptide with good activity against GramPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G., Monaim S.A.H.A., Ramchuran E.J.Fuentes:scopusMicrowave-Assisted Green Solid-Phase Peptide Synthesis Using γ-Valerolactone (GVL) as Solvent
ArticleAbstract: The increasing demand for synthetic peptides in various research fields raises a challenge, namely,Palabras claves:Automatic synthesis, Green solvent, peptide, Sustainable chemistryAutores:Alberício F., B. G. De la Torre, Collins J.M., Jad Y.E., Kumar A.Fuentes:scopusPeptide synthesis beyond DMF: THF and ACN as excellent and friendlier alternatives
ArticleAbstract: To date, DMF has been considered as the only solvent suitable for peptide synthesis. Here we demonstPalabras claves:Autores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopus