Mostrando 10 resultados de: 24
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British Journal of Pharmacology(3)
Neuroscience(3)
Journal of Alzheimer's Disease(2)
Annals of the New York Academy of Sciences(1)
Apoptosis(1)
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Enfermedades(19)
Fisiología humana(12)
Farmacología y terapéutica(10)
Bioquímica(7)
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scopus(24)
C-phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis
ArticleAbstract: We tested the potential cytoprotective role of C-phycocyanin in rat cerebellar granule cell culturesPalabras claves:apoptosis, C-Phycocyanin, cell cycle, Cerebellar granule cells, Flow cytometry, Laser scanning cytometry, Oxidative Stress, RATAutores:Antoni Camins, Camarasa J., Escubedo E., González R., Jiménez A., Pallás M., Pubill D., Rimbau V., Romay C., Sureda F.X.Fuentes:scopusAntiapoptotic effects of roscovitine in cerebellar granule cells deprived of serum and potassium: A cell cycle-related mechanism
ArticleAbstract: Neuronal apoptosis may be partly due to inappropriate control of the cell cycle. We used serum depriPalabras claves:apoptosis, Caspase-3, cell cycle, cyclin, E2F-1, RoscovitineAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Verdaguer E.Fuentes:scopus(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopus3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons
ArticleAbstract: The mechanisms underlying selective neuronal cell death in kainic acid-mediated neurodegeneration arPalabras claves:cell cycle, Cyclin-dependent kinases, Excitotoxicity, Neurodegenerative illnessAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusCyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: 1 Cyclosporin A (CsA, 1-50 μM), an immunosuppressive drug with known neurotoxic effects, did not decPalabras claves:CDK5, colchicine, Cyclosporin A, flavopiridol, Neurotoxicity, RoscovitineAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusEvaluation of neuronal cell death by laser scanning cytometry
ArticleAbstract: We developed a method in which laser scanning cytometry (LSC) is applied to evaluate cell viability.Palabras claves:Autores:Antoni Camins, Camarasa J., Escubedo E., Jiménez A., Pallás M., Pubill D., Rimbau V., Verdaguer E.Fuentes:scopusEvaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis
ArticleAbstract: The cytoskeleton is critical to neuronal functioning and survival. Cytoskeletal alterations are invoPalabras claves:calcium, Calpainsl, Caspases, Cytoskeleton, Serine-proteasesAutores:Allgaier C., Antoni Camins, Arriba S.G.D., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusEvidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis
ArticleAbstract: The mitochondrial peripheral benzodiazepine receptor (PBR) is involved in a functional structure desPalabras claves:AIF, Cerebellar granule cells, colchicine, Cyt c, Mitochondrial permeability transition, Peripheral benzodiazepine receptorAutores:Antoni Camins, Canudas A.M., Folch J., Jiménez A., Jordá E.G., Pallás M., Sureda F.X., Verdaguer E.Fuentes:scopusNeuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8)
ArticleAbstract: Senescence-accelerated mice 8 (SAMP8), a model of aging, display many established pathological featuPalabras claves:aging, Alzheimer's disease, CDK5, cell cycle, GSK3β, TauAutores:Antoni Camins, Casadesús G., Gutiérrez-Cuesta J., Jiménez A., Lee H.g., Ortuo-Sahagún D., Pallás M., Smith M.A., Tajes M.Fuentes:scopusNeuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis
ArticleAbstract: Flavopiridol was developed as a drug for cancer therapy due to its ability to inhibit cell cycle proPalabras claves:Caspase-3, Cerebellar granule neurons, Cyclin-dependent kinases, flavopiridol, neuroprotection, Par-4Autores:Antoni Camins, Bravo R., Bruna A., Caelles C., Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Verdaguer E.Fuentes:scopus