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Breaking a Couple: Disulfide Reducing Agents
ReviewAbstract: Cysteine is present in a large number of natural and synthetic (bio)molecules. Although the thiol siPalabras claves:Cysteine, cystine, Disulfide bridges, reducing agents, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, Mthembu S.N., Sharma A.Fuentes:scopusBypassing osmotic shock dilemma in a polystyrene resin using the green solvent cyclopentyl methyl ether (CPME): A morphological perspective
ArticleAbstract: The "osmotic shock" phenomenon is the main thing that is responsible for morphological structure altPalabras claves:Green solvent, Osmotic shock, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., Almarhoon Z.M., B. G. De la Torre, Basso A., El-Faham A.Fuentes:scopusAnalytical methodologies to assure successful peptide synthesis when utilizing polystyrene/DVB resins
ArticleAbstract: Solid-phase peptide synthesis has become an important technique as the method of choice to deliver hPalabras claves:Fluorenylmethoxycarbonyl (Fmoc), Functionalization, MORPHOLOGY, Peer Reviewed, Polystyrene resins, Solid support, Solid-phase peptide synthesis, swellingAutores:Al Musaimi O., Alberício F., Alhassan M., B. G. De la Torre, Basso A., Serban S., Summers B.D.Fuentes:scopus2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis
ArticleAbstract: 2-MeTHF and CPME were evaluated as greener alternatives for the most employed solvents in peptide syPalabras claves:2-methyltetrahydrofuran, Cyclopentyl methyl ether, Green solvents, Peptide synthesis, Solid-phase peptide synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopus2017 FDA peptide harvest
ReviewAbstract: 2017 was an excellent year in terms of new drugs (chemical entities and biologics) approved by the FPalabras claves:Drug Discovery, drugs, Pharmaceutical market, Solid-phase peptide synthesisAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusA Practical Peptide Synthesis Workflow Using Amino-Li-Resin
ArticleAbstract: Herein we report a practical approach for peptide synthesis using second-generation fibrous polyacryPalabras claves:amino-Li-resin, gravity filtration, shaking, Solid-phase peptide synthesisAutores:Akintayo D.C., Alberício F., B. G. De la Torre, Li Y., Manne S.R.Fuentes:scopusA convenientmicrowave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides
ArticleAbstract: Structural modification of the peptide backbone via N-methylation is a powerful tool to modulate thePalabras claves:Fmoc-N-methyl amino acids, MICROWAVE, Solid-phase peptide synthesisAutores:Alberício F., Hortensia Rodriguez Cabrera, Suárez Navarro M.Fuentes:scopusAmino-Li-Resin—A Fiber Polyacrylamide Resin for Solid-Phase Peptide Synthesis
ArticleAbstract: Amino-Li-resin is a new and unique polyacrylamide resin presented in the form of fibers and is foundPalabras claves:amino-Li-resin, fibers, Polyacrylamide, Solid-phase peptide synthesisAutores:Akintayo D.C., Alberício F., B. G. De la Torre, Li Y.Fuentes:scopusGREEN CIRCULAR ECONOMY APPLIED TO PEPTIDE SYNTHESIS
ArticleAbstract: While the focus of industry was once to cover people’s needs, it is now imperative to address how toPalabras claves:Circular economy, Green Chemistry, Oligonucleotides, recycling, redesigning, Solid-phase peptide synthesis, SustainabilityAutores:Alberício F., B. G. De la Torre, Musaimi O.A.L., Shaer D.A.L.Fuentes:scopusGreen Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry
ArticleAbstract: DMF (N,N-dimethylformamide) is the most widely used solvent for Fmoc-SPPS, which is the conventionalPalabras claves:Fmoc, Green solvents, Peptide aggregation, Protecting groups, Solid-phase peptide synthesis, valerolactoneAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopus