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Antitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2)
ArticleAbstract: Protein Kinase (casein kinase 2, CK2) is a serine-threonine kinase that is frequently dysregulated iPalabras claves:Autores:Acevedo B.E., Alonso D.F., Falcón-Cama V., López-Mola E., Mendoza O., Perea-Rodríguez S.E., Puchades Y., Reyes O., Santiago Nelson Vispo, Santos-Savio A., Silva R., Torrens I.Fuentes:scopusDevelopment and validation of a bioanalytical LC-MS method for the quantification of GHRP-6 in human plasma
ArticleAbstract: Growth hormone-releasing peptide 6 (GHRP-6, His-(DTrp)-Ala-Trp-(DPhe)-Lys-NH 2, MW=872.44Da) is a poPalabras claves:GHRP-6, internal standard, LC-MS, Method validation, PlasmaAutores:Besada-Pérez V., Betancourt L., Cabrales A., García G., Gil J., González L.J., Moya G., Padrón G., Reyes O., Sánchez A., Vivian Morera CórdovaFuentes:scopusCIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusProtective immune response against Neisseria meningitidis serogroup B after immunization with peptides mimicking a capsular polysaccharide epitope
ArticleAbstract:Palabras claves:Autores:Brown E., Caballero E., Carmenate T., Chinea G., Cobas K., Coizeau E., Cruz Y., Garay H.E., González S., Guillén-Nieto G.E., Martín A., Menéndez T., Noda J., Reyes O., Santiago Nelson Vispo, Soria Y., Vivian Morera Córdova, Yero D.Fuentes:scopusSolid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro- 2H-1,3,5-thiadiazin-2-thione derivatives
ArticleAbstract: The solid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro-2H-1,3,5-thiadiazin-2-thiPalabras claves:Resins amino acids, solid-phase synthesis, Thiadiazin-2-thionesAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Molero-Vilchez M.D., Ochoa C., Perez-Pineiro R., Reyes O., Suárez Navarro M.Fuentes:googlescopusSolid-phase synthesis of 4-aryl substituted 5-carboxy-6-methyl-3,4-dihydropyridones
ArticleAbstract: Substituted 3,4-dihydro-2-pyridones have been efficiently prepared by solid-phase synthesis using WaPalabras claves:5-Carboxy-6-methyl-3,4-dihydropyridones, solid-phase synthesis, Wang resinAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Martín N., Perez-Pineiro R., Reyes O., Seoane C., Suárez Navarro M., Verdecia Y.Fuentes:googlescopusStudy of various presentation forms for a peptide mimetic of Neisseria meningitidis serogroup B capsular polysaccharide
ArticleAbstract: The formulation of a broadly protective vaccine to prevent the serogroup B Neisseria meningitidis (MPalabras claves:Autores:Alberício F., Coizeau E., Cruz-Leal Y., Garay H.E., Guillén-Nieto G.E., Menéndez T., Noda J., Reyes O., Vivian Morera CórdovaFuentes:scopusStudy on the decomposition products of thiadiazinthione and their anticancer properties
ArticleAbstract: Study of the anticancer properties of thirty-four 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2Palabras claves:Anticancer drugs, N,N-Disubstituted tetrahydro-1,3,5-thiadiazin-2-thione derivatives, anticancer properties, decomposition products, synthesisAutores:Ezpelata O., Gonzalez L.J., Hortensia Rodriguez Cabrera, Lopez de Cerain A., Ochoa C., Pérez C., Perez E., Pérez R., Reyes O., Suárez Navarro M.Fuentes:googlescopus