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Bio-analytical method based on MALDI-MS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma
ArticleAbstract: A fully validated bio-analytical method based on Matrix-Assisted-Laser-Desorption/Ionization-Time ofPalabras claves:Anti-tumor peptide, Bio-analytical method, Full validation, Human plasma, Maldi-tofAutores:Audain E., B. G. De la Torre, Besada-Pérez V., Cabrales-Rico A., Garay H.E., Gómez J.A., González L.J., Machado Y.J., Marcelo J.L., Morales O., Perea-Rodríguez S.E., Perera Y., Reyes O., Reyes V.Fuentes:scopusAntitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2)
ArticleAbstract: Protein Kinase (casein kinase 2, CK2) is a serine-threonine kinase that is frequently dysregulated iPalabras claves:Autores:Acevedo B.E., Alonso D.F., Falcón-Cama V., López-Mola E., Mendoza O., Perea-Rodríguez S.E., Puchades Y., Reyes O., Santiago Nelson Vispo, Santos-Savio A., Silva R., Torrens I.Fuentes:scopusDevelopment and validation of a bioanalytical LC-MS method for the quantification of GHRP-6 in human plasma
ArticleAbstract: Growth hormone-releasing peptide 6 (GHRP-6, His-(DTrp)-Ala-Trp-(DPhe)-Lys-NH 2, MW=872.44Da) is a poPalabras claves:GHRP-6, internal standard, LC-MS, Method validation, PlasmaAutores:Besada-Pérez V., Betancourt L., Cabrales A., García G., Gil J., González L.J., Moya G., Padrón G., Reyes O., Sánchez A., Vivian Morera CórdovaFuentes:scopusSolid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro- 2H-1,3,5-thiadiazin-2-thione derivatives
ArticleAbstract: The solid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro-2H-1,3,5-thiadiazin-2-thiPalabras claves:Resins amino acids, solid-phase synthesis, Thiadiazin-2-thionesAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Molero-Vilchez M.D., Ochoa C., Perez-Pineiro R., Reyes O., Suárez Navarro M.Fuentes:googlescopusSolid-phase synthesis and structural study of substituted 1,4,5,6-tetrahydro-6-oxopyridine-3-carboxylic acids
ArticleAbstract: An efficient solid-phase approach to prepare substituted 1,4,5,6-tetrahydro-6-oxopyridines bearing aPalabras claves:1,4,5,6-Tetrahydro-6-oxopyridine-3-carboxylic acids, B3LYP/6-31G* theoretical calculations, solid-phase synthesis, Wang resinAutores:Alberício F., Garay H.E., Hortensia Rodriguez Cabrera, Martín N., Martín O., Ochoa E., Reyes O., Suárez Navarro M.Fuentes:scopusSolid-phase synthesis of 4-aryl substituted 5-carboxy-6-methyl-3,4-dihydropyridones
ArticleAbstract: Substituted 3,4-dihydro-2-pyridones have been efficiently prepared by solid-phase synthesis using WaPalabras claves:5-Carboxy-6-methyl-3,4-dihydropyridones, solid-phase synthesis, Wang resinAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Martín N., Perez-Pineiro R., Reyes O., Seoane C., Suárez Navarro M., Verdecia Y.Fuentes:googlescopusStudy on the decomposition products of thiadiazinthione and their anticancer properties
ArticleAbstract: Study of the anticancer properties of thirty-four 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2Palabras claves:Anticancer drugs, N,N-Disubstituted tetrahydro-1,3,5-thiadiazin-2-thione derivatives, anticancer properties, decomposition products, synthesisAutores:Ezpelata O., Gonzalez L.J., Hortensia Rodriguez Cabrera, Lopez de Cerain A., Ochoa C., Pérez C., Perez E., Pérez R., Reyes O., Suárez Navarro M.Fuentes:googlescopusUnconventional synthesis of nitrogenated heterocycles with potencial bioactive properties
ArticleAbstract:Palabras claves:Autores:Hortensia Rodriguez Cabrera, Martín O., Ochoa E., Reyes O., Suárez Navarro M.Fuentes:googlescopus