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GSK3β interactions with amyloid genes: an autopsy verification and extension
OtherAbstract: Glyocogen synthase kinase 3 (GSK3) plays an important role in the pathophysiology of Alzheimer’s disPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size
OtherAbstract: The genetic etiology of late-onset Alzheimer’s disease (LOAD) has proven complex, involving clinicalPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic resilience to amyloid related cognitive decline
OtherAbstract: Preclinical Alzheimer’s disease (AD) is characterized by amyloid deposition in the absence of overtPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic variation modifies risk for neurodegeneration based on biomarker status
OtherAbstract: Background: While a great deal of work has gone into understanding the relationship between CerebrosPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleEpistatic genetic effects among Alzheimer’s candidate genes
OtherAbstract: Background Novel risk variants for late-onset Alzheimer’s disease (AD) have been identified and replPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleP4‐094: EXOME‐WIDE ANALYSIS IDENTIFIES NOVEL SEX‐SPECIFIC CANDIDATE GENES FOR ALZHEIMER DISEASE
OtherAbstract: Background Women comprise nearly two-thirds of all Alzheimer disease (AD) cases, suggesting gender-sPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleInteractions between GSK3β and amyloid genes explain variance in amyloid burden
OtherAbstract: The driving theoretical framework of Alzheimer's disease (AD) has been built around the amyloid-β (APalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleSex differences in the genetic pbkp_redictors of Alzheimer’s pathology
OtherAbstract: Autopsy measures of Alzheimer’s disease neuropathology have been leveraged as endophenotypes in prevPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:google[P4–085]: SYNAPTONEMAL COMPLEX PROTEIN 2 LIKE GENE PROTECTS AGAINST HIPPOCAMPAL ATROPHY AND MEMORY DECLINE
OtherAbstract: Background Alzheimer's disease is characterized by progressive neurodegeneration and cognitive impaiPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:google