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Co-delivery of hydrophobic and hydrophilic drugsfrom nanoparticle-aptamer bioconjugates
ArticleAbstract: (Figure Presented) Herein we report a novel targeted drug delivery system consisting of nanoparticlePalabras claves:Antitumor agents, conjugation, Dual drug delivery, Nanoparticles, Targeted therapyAutores:Bagalkot V., Basto P.A., Farokhzad O.C., Frank Alexis, Gu F.X., Jon S., Langer R.S., Radovic-Moreno A.F., Zhang L.Fuentes:scopusA closer look to polyesters: Properties, synthesis, characterization, and particle drug delivery applications
ReviewAbstract: Background: Natural and synthetic polymeric materials can be used in the fields of bio-medicine andPalabras claves:Biodegradable, drug delivery, Microparticles, Nanoparticles, Polyesters, polymersAutores:Debut Alexis, Dr Brajesh Kumar, Frank Alexis, Karla Vizuete, Katherine Pazmiño ViteriFuentes:scopusFunctionalized nanoparticles containing MKP-1 agonists reduce periodontal bone loss
ArticleAbstract: Background: Progress over of the past several years has elucidated a role for mitogen-activated protPalabras claves:alveolar bone, auranofin, inflammation, Nanoparticles, periodonticsAutores:Frank Alexis, Kirkwood K.L., Valerio M.S.Fuentes:scopusFactors affecting the biological response of Graphene
ReviewAbstract: Nanotechnology has gained significant importance in different fields of medical, electronic, and envPalabras claves:2d materials, Biomedical, Carbon nanomaterials, Graphene oxide, NanoparticlesAutores:Camilo Zamora-Ledezma, Costa B., de Oliveira Vieira T., Frank Alexis, Hu R., Magne T.M., Qu J., Rebelo Alencar L.M., Ricci-Junior E., Santos-Oliveira R.Fuentes:scopusEngineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection
ArticleAbstract: Figure Persented: One of the major challenges in the development of targeted nanoparticles (NPs) forPalabras claves:aptamer, in vitro selection, Internalization, Nanoparticles, targeted cancer therapyAutores:Chan J.M., Cheng J., Digga E., Farokhzad O.C., Frank Alexis, Langer R.S., Levy-Nissenbaum E., Lupták A., Shi J., Teply B.A., Xiao Z.Fuentes:scopusHER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy
ArticleAbstract: (Figure Presented) Affibodies are a class of polypeptide ligand that are potential candidates for tiPalabras claves:Affibodies, Antitumor agents, Nanoparticles, PLA-PEG copolymers, Targeted therapyAutores:Basto P.A., Farokhzad O.C., Frank Alexis, Levy-Nissenbaum E., Marein S.L., Molnar L.K., Pridgen E.M., Radovic-Moreno A.F., Wang A.Z., Westerhof K., Zhang L.Fuentes:scopusMolecular and cellular risk assessment of healthy human cells and cancer human cells exposed to nanoparticles
ArticleAbstract: Nanodrugs have in recent years been a subject of great debate. In 2017 alone, almost 50 nanodrugs wePalabras claves:cell culture, Nanomedicine, Nanoparticles, Primary cells, Tumor cellAutores:Barja-Fidalgo C., Brandão-Costa R., de Barros A.O.d.S., dos Santos C.C., Frank Alexis, Helal-Neto E., Martínez-Máñez R., Morandi V., Rebelo Alencar L.M., Ricci-Junior E., Saldanha-Gama R., Santos-Oliveira R.Fuentes:scopusRadioactive polymeric nanoparticles for biomedical application
ArticleAbstract: Nowadays, emerging radiolabeled nanosystems are revolutionizing medicine in terms of diagnostics, trPalabras claves:Medical Imaging, Nanoparticles, nanoradiopharmaceuticals, polymers, radionuclidesAutores:Alves Junior S., Carolina Serrano-Larrea, Frank Alexis, Helal-Neto E., Jafari A., Kozempel J., Matos A.P.d.S., Ricci-Junior E., Santos-Oliveira R., Silva Y.J.d.A., Wu S.Fuentes:scopusRadiopharmacokinetics of Graphene Quantum Dots Nanoparticles In vivo: Comparing the Pharmacokinetics Parameters in Long and Short Periods
ArticleAbstract: Background: Nanoparticles (NPs) have gained great importance during the last decades for developingPalabras claves:99m Tc labeling, GQDs, graphene quantum dots, In vivo analyses, Nanoparticles, pharmacokineticsAutores:Alencar L.M.R., Attia M.F., Bastos M.K., Fechine P.B.d.A., Frank Alexis, Gemini-Piperni S., Matos A.P.d.S., Pijeira M.S.O., Ricci-Junior E., Santos-Oliveira R., Sobrinho J.H.d.S.Fuentes:scopusPolymer-Scaffolded Synthesis of Periodic Mesoporous Organosilica Nanomaterials for Delivery Systems in Cancer Cells
ArticleAbstract: We developed four types of para-phenylene-bridged periodic mesoporous organosilica NPs (p-P PMO NPs)Palabras claves:Cáncer, drug delivery, imaging, Nanoparticles, periodic mesoporous organosilicaAutores:Akasov R., Attia M.F., Frank Alexis, Whitehead D.C.Fuentes:scopus