Mostrando 10 resultados de: 22
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scopus(22)
(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopus3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons
ArticleAbstract: The mechanisms underlying selective neuronal cell death in kainic acid-mediated neurodegeneration arPalabras claves:cell cycle, Cyclin-dependent kinases, Excitotoxicity, Neurodegenerative illnessAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusCharacterization of nitrobenzylthioinosine binding sites in the mitochondrial fraction of rat testis
ArticleAbstract: The presence of [3H] NBMPR binding sites in the mitochondrial fraction of rat testis is described. TPalabras claves:Mitochondrial fraction, Nitrobenzylthioinosine binding sites, TestisAutores:Antoni Camins, Camarasa J., Escubedo E., Jiménez A., Pallás M., Sureda F.X.Fuentes:scopusAntiapoptotic effects of roscovitine in cerebellar granule cells deprived of serum and potassium: A cell cycle-related mechanism
ArticleAbstract: Neuronal apoptosis may be partly due to inappropriate control of the cell cycle. We used serum depriPalabras claves:apoptosis, Caspase-3, cell cycle, cyclin, E2F-1, RoscovitineAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Verdaguer E.Fuentes:scopusEffects of melatonin in the brain of the senescence-accelerated mice-prone 8 (SAMP8) model
ArticleAbstract: Summary. Senescence-accelerated mice (SAM) represent an aging model establish by selective inbreedinPalabras claves:CDK5, GSK3beta, melatonin, TauAutores:Antoni Camins, Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopusFurther characterization of an adenosine transport system in the mitochondrial fraction of rat testis
ArticleAbstract: Previous work from our laboratory has demonstrated the presence of high- affinity binding sites forPalabras claves:Adenosine uptake, Benzodiazepine receptor ligand, mitochondrial, Mitochondrion, Testis, rat, [ H]Adenosine 3Autores:Antoni Camins, Camarasa J., Escubedo E., Jiménez A., Lladó S., Pallás M., Pubill D.Fuentes:scopusFlavopiridol: An antitumor drug with potential application in the treatment of neurodegenerative diseases
ArticleAbstract: Several lines of evidence show that cyclin-dependent kinases (CDKs) contribute to neurodegenerativePalabras claves:Autores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusImplication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium
ArticleAbstract: Although numerous studies have demonstrated a neuroprotective and anti-apoptotic role of lithium inPalabras claves:apoptosis, Cdk5/p25, Cerebellar granule neurons, GSK-3β, LithiumAutores:Allgaier C., Antoni Camins, Canudas A.M., Garcia De Arriba S., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusEvaluation of neuronal cell death by laser scanning cytometry
ArticleAbstract: We developed a method in which laser scanning cytometry (LSC) is applied to evaluate cell viability.Palabras claves:Autores:Antoni Camins, Camarasa J., Escubedo E., Jiménez A., Pallás M., Pubill D., Rimbau V., Verdaguer E.Fuentes:scopusEvaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model
ArticleAbstract: We examined the effect of melatonin on pro-survival processes in three groups of mice. Untreated senPalabras claves:aging, Amyloid β, BRAIN, Cysteine proteases, Sirt1Autores:Antoni Camins, Coto-Montes A., Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopus