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A study of the electrospray ionisation and ion-trap fragmentation of [M - H]<sup>-</sup> ions of new 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazin-2-thiones
ArticleAbstract: The electrospray ionisation (ESI) in negative mode of the pharmacologically significant 3,5-disubstiPalabras claves:Autores:Hortensia Rodriguez Cabrera, Kayali N., Martín N., Martínez-Álvarez R., Perez-Pineiro R., Seoane C., Suárez Navarro M.Fuentes:scopusAlkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents
ArticleAbstract: The effect of several alkyl-linked bis tetrahydro-(2H)-1,3,5-thiadiazine-2- thione (bis-THTT) on LeiPalabras claves:Alkyl-linked bis-THTT anti-protozoal activityAutores:Alvarez A., Atherton R., Coro J., Hortensia Rodriguez Cabrera, Little S., Perez-Pineiro R., Suárez Navarro M., Wharton H., Yardley V.Fuentes:googlescopusAlkylation of some pyrimidine and purine derivatives using microwave-assisted methods
ArticleAbstract: N-Alkylation of adenine (1), guanine (2) and 6-amino-2-thiouracil (3) with different halides has beePalabras claves:Autores:Cabrales N., Hortensia Rodriguez Cabrera, Lam A., Loupy A., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusDevelopment of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
ArticleAbstract: The implementation of a novel sequential computational approach that can be used effectively for virPalabras claves:Autores:Andrew L.C., Burgos A., Fairlamb A.H., Hortensia Rodriguez Cabrera, Jones D.C., Perez-Pineiro R., Suárez Navarro M., Wishart D.S.Fuentes:googlescopusIn vitro activities of thiadiazine derivatives against Leishmania amazonensis
ArticleAbstract: Ten thiadiazine derivatives were tested in vitro for antiparasitic effects against both extracellulaPalabras claves:Antiparasitic drugs, Leishmania amazonensis, amastigotes, promastigotes, Thiadiazine derivatives, antileishmanial activity in vitro, toxicityAutores:Fonseca L., Hortensia Rodriguez Cabrera, Montalvo Álvarez A.M., Monzote L., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusIn vitro and in vivo assays of 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives against Trypanosoma cruzi
ArticleAbstract: Cytotoxicity assays of 24 new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivativesPalabras claves:AMASTIGOTES, Antichagasic drugs, Antitrypanosomal activity assays, Cytotoxicity assays, J774 macrophages, Thiadiazine thione derivativesAutores:García-Trevijano J.A.E., Gómez-Barrio A., Hortensia Rodriguez Cabrera, Muelas S., Ochoa C., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusQuantitative structured antitumoral-activity relationships of thiadiazinthione derivatives using the novel hybrid molecular index <sup>p</sup>MR<inf>χ</inf>
ArticleAbstract: Purpose. The recently defined molarrefractivity-partition index was applied to a family of 1,3,5- thPalabras claves:Autores:Carrasco R., Hortensia Rodriguez Cabrera, Ochoa C., Padrón J.A., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusSolid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro- 2H-1,3,5-thiadiazin-2-thione derivatives
ArticleAbstract: The solid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro-2H-1,3,5-thiadiazin-2-thiPalabras claves:Resins amino acids, solid-phase synthesis, Thiadiazin-2-thionesAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Molero-Vilchez M.D., Ochoa C., Perez-Pineiro R., Reyes O., Suárez Navarro M.Fuentes:googlescopusSolid-phase synthesis of 4-aryl substituted 5-carboxy-6-methyl-3,4-dihydropyridones
ArticleAbstract: Substituted 3,4-dihydro-2-pyridones have been efficiently prepared by solid-phase synthesis using WaPalabras claves:5-Carboxy-6-methyl-3,4-dihydropyridones, solid-phase synthesis, Wang resinAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Martín N., Perez-Pineiro R., Reyes O., Seoane C., Suárez Navarro M., Verdecia Y.Fuentes:googlescopusSpectral Assignments and Reference Data<sup>1</sup>H and<sup>13</sup>C NMR spectral assignments for 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives
ArticleAbstract: The proton and carbon spectra of 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatiPalabras claves:1 H NMR, 1,3,5-thiadiazine-2-thione, 13 C NMR, NMRAutores:Hortensia Rodriguez Cabrera, Martín N., Martinez R., Molero D., Perez-Pineiro R., Seoane C., Suárez Navarro M.Fuentes:scopus