Mostrando 10 resultados de: 12
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Monatshefte fur Chemie(5)
Amino Acids(2)
Arkivoc(1)
European Journal of Organic Chemistry(1)
Journal of Fluorine Chemistry(1)
A new approach to N-methylaspartic, N-methylglutamic, and N-methyl-α- aminoadipic acid derivatives
ArticleAbstract: N-Methylaspartic acid derivatives and its homologues are obtained by a stereoconservative one-pot prPalabras claves:Hexafluoroacetone, N-Methyl- α-aminoadipic acid, N-Methylaspartic acid, N-Methylglutamic acid, N-Methylthiazol-4-yl-α-amino acidsAutores:Burger K., Jan SpenglerFuentes:scopusA new protection/activation strategy for the synthesis of naturally occurring and non-natural α-N-alkylamino acids
ReviewAbstract: A new method for the preparation of N-methylamino acids and some of their derivatives starting fromPalabras claves:amino acids, Hexafluoroacetone, Pro-Glu-chimeras, Pro-Tau-chimeras, α-N-methylamino acids, α-N-phosphinoylmethylamino acidsAutores:Burger K., Jan Spengler, Schedel H.Fuentes:googlescopusApplication of hexafluoroacetone as protecting and activating reagent in solid phase peptide and depsipeptide synthesis
ArticleAbstract: Hexafluoroacetone-protected/activated hydroxy acids [2,2- bis(trifluoromethyl)-1,3-dioxolan-4-ones]Palabras claves:Bidentate reagents, Citramalic acid, Hexafluoroacetone, Tetrahydroisoquinoline carboxylic acidAutores:Alberício F., Burger K., Cupido T., Jan Spengler, Ruiz J.Fuentes:googlescopusHexafluoroacetone as a protecting and activating reagent. N- and O-glycosylation of isoserine and isocysteine *
ArticleAbstract: Starting from HFA-protected malic and thiomalic acid a series of O- and N-glycoconjugates suitable fPalabras claves:Glycoconjugates, Glycosylamines, Hexafluoroacetone, Isocyanates, malic acid, Thiomalic acidAutores:Alberício F., Böttcher C., Burger K., Hennig L., Jan SpenglerFuentes:googlescopusHexafluoroacetone as a protecting and activating reagent. Regioselective esterification of aspartic, malic, and thiomalic acid
ArticleAbstract: Hexafluoroacetone reacts with α-functionalized α,β- dicarboxy acids like aspartic, malic, and thiomaPalabras claves:Branched depsipeptides, Branched peptides, Hexafluoroacetone, Peptidomimetics, polyesterAutores:Alberício F., Burger K., Jan Spengler, Pumpor K., Windeisen E.Fuentes:googlescopusHexafluoroacetone as protecting and activating reagent. A new approach to N-glycosides
ArticleAbstract: N-Glycosides of Asn and homologues have been synthesized starting from hexafluoroacetone-protected ωPalabras claves:Dielectrophiles, Hexafluoroacetone, N-Glycopeptides, N-Glycosylamino acids, N-glycosylationAutores:Böttcher C., Burger K., Essawy S.A., Jan SpenglerFuentes:googlescopusHexafluoroacetone as protecting and activating reagent: Reactions of hexafluoroacetone with α-keto acids
ArticleAbstract: Hexafluoroacetone and α-keto acids react to give 5,5-bis(trifluoromethyl) substituted 2(5H)-furanonePalabras claves:2,2-Bis(trifluoromethyl)-1,3-dioxolan-4-ones, 5,5-Bis(trifluoromethyl)-2(5H)-furanones, 5-Trifluoromethyl-2(5H)-furanones, Butenolides, Hexafluoroacetone, Zymonic acid, α-Keto acidsAutores:Burger K., Haas A., Heistracher E., Jan Spengler, Osipov S.N.Fuentes:googlescopusOrthogonally protected, carboxy-activated L-homoisoserine, 2-methyl-L-homoisoserine, and homoisocysteine derivatives. New building blocks for peptide and depsipeptide modification
ArticleAbstract: Starting from L-malic, L-citramalic, and rac. thiomalic acids routes to L-homoisoserine, 2-methyl-L-Palabras claves:Arndt-Eistert reaction, Azapeptides, Citramalic acid, Curtius rearrangement, Depsipeptide modification, Hexafluoroacetone, malic acid, Peptide modification, Thiomalic acid, Wolff rearrangement, α-Hydroxy acids, α-Mercapto acids, γ-Amino acidsAutores:Alberício F., Böttcher C., Burger K., Hennig L., Jan Spengler, Radics G.Fuentes:googlescopusIncorporation of the α-mercapto acid unit into peptides
ArticleAbstract: Incorporation of α-mercapto acid units into the backbone of potential drug candidates improves the mPalabras claves:Acylations, Dielectrophiles, Hexafluoroacetone, Peptides, Thiols, Thiomalic acidAutores:Alberício F., Burger K., Haas A., Jan Spengler, Pumpor K.Fuentes:googlescopusL-α-Methylhomoisoserine: A New Versatile Building Block for Peptide and Depsipeptide Modification
ArticleAbstract: An efficient access to L-α-methylhomoisoserine derivatives starting from L-citramalic acid is descriPalabras claves:Amino acid hydroxamates, Arndt-Eistert synthesis, Citramalic acid, Curtius rearrangement, Hexafluoroacetone, Wolff rearrangement, γ-amino-α-hydroxy-α -methylbutyric acidAutores:Burger K., El-Kousy S.M., Jan Spengler, Koksch B., Radics G.Fuentes:googlescopus