Mostrando 7 resultados de: 7
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Monatshefte fur Chemie(2)
Amino Acids(1)
Chemical Reviews(1)
Journal of Fluorine Chemistry(1)
Journal of Organic Chemistry(1)
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Farmacología y terapéutica(1)
Ingeniería química(1)
Química física(1)
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A new protection/activation strategy for the synthesis of naturally occurring and non-natural α-N-alkylamino acids
ReviewAbstract: A new method for the preparation of N-methylamino acids and some of their derivatives starting fromPalabras claves:amino acids, Hexafluoroacetone, Pro-Glu-chimeras, Pro-Tau-chimeras, α-N-methylamino acids, α-N-phosphinoylmethylamino acidsAutores:Burger K., Jan Spengler, Schedel H.Fuentes:googlescopusA novel protecting/activating strategy for β-hydroxy acids and its use in convergent peptide synthesis
ArticleAbstract: (Chemical Equation Presented) β-Hydroxy acids were reacted with hexafluoroacetone and carbodiimidesPalabras claves:Autores:Alberício F., Burger K., Jan Spengler, Royo M., Ruíz-Rodríguez J., Winter M., Yraola F.Fuentes:googlescopusNO as temporary guanidino-protecting group provides efficient access to Pbf-protected argininic acid
ArticleAbstract: Pbf-protected argininic acid [H-OArg(Pbf)-OH], a building block for Fmoc-solid phase peptide synthesPalabras claves:arginine, Depsipeptides, side-reactions, Solid phase peptide synthesisAutores:Alberício F., Burger K., Cupido T., Jan SpenglerFuentes:googlescopusHexafluoroacetone as protecting and activating reagent. A new approach to N-glycosides
ArticleAbstract: N-Glycosides of Asn and homologues have been synthesized starting from hexafluoroacetone-protected ωPalabras claves:Dielectrophiles, Hexafluoroacetone, N-Glycopeptides, N-Glycosylamino acids, N-glycosylationAutores:Böttcher C., Burger K., Essawy S.A., Jan SpenglerFuentes:googlescopusHexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design
ArticleAbstract: Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiPalabras claves:3-Hydroxysuccinimido sugars, Dielectrophiles, Glycosylamines, Maleimido sugars, N-Glycosylated depsipeptides, α-Hydroxy acids, α-Hydroxyacylamino acids, α-Mercapto acids, α-Mercaptoacylamino acidsAutores:Böttcher C., Burger K., Jan SpenglerFuentes:googlescopusHexafluoroacetone as protecting and activating reagent: New routes to amino, hydroxy, and mercapto acids and their application for peptide and glyco- and depsipeptide modification
ArticleAbstract: A critical overview is given of the synthetic potential of hexafluoroacetone (HFA) as bidentate reagPalabras claves:Autores:Alberício F., Böttcher C., Burger K., Jan SpenglerFuentes:googlescopusHexafluoroacetone as protecting and activating reagent: Reactions of hexafluoroacetone with α-keto acids
ArticleAbstract: Hexafluoroacetone and α-keto acids react to give 5,5-bis(trifluoromethyl) substituted 2(5H)-furanonePalabras claves:2,2-Bis(trifluoromethyl)-1,3-dioxolan-4-ones, 5,5-Bis(trifluoromethyl)-2(5H)-furanones, 5-Trifluoromethyl-2(5H)-furanones, Butenolides, Hexafluoroacetone, Zymonic acid, α-Keto acidsAutores:Burger K., Haas A., Heistracher E., Jan Spengler, Osipov S.N.Fuentes:googlescopus